Powder: -20°C for 3 years | In solvent: -80°C for 1 year
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | Inquiry | |
50 mg | 6-8 weeks | Inquiry | |
100 mg | 6-8 weeks | Inquiry |
Description | APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling. |
Molecular Weight | 387.43 |
Formula | C23H21N3O3 |
CAS No. | 2002381-25-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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APS-2-79 2002381-25-9 LY-3325656 LY 3325656 inhibitor inhibit