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3-Methyl-GABA

Catalog No. T22509 CAS 1216629-00-3

3-Methyl-GABA is a potent GABA aminotransferase activator. 3-Methyl-GABA can fit the binding pocket of GABA A receptor (GABAaR). 3-Methyl-GABA can activate L-glutamic acid decarboxylase (GAD). 3-Methyl-GABA is an anticonvulsant agent [1] [2].

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3-Methyl-GABA, CAS 1216629-00-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	3-Methyl-GABA is a potent GABA aminotransferase activator. 3-Methyl-GABA can fit the binding pocket of GABA A receptor (GABAaR). 3-Methyl-GABA can activate L-glutamic acid decarboxylase (GAD). 3-Methyl-GABA is an anticonvulsant agent [1] [2].
In vitro	The GAD activation is stereoselective for the R isomer of 3-methyl GABA compared to the corresponding S isomer [1].

Molecular Weight	522.59
Formula	C20H30N2O10S2
CAS No.	1216629-00-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

H2O: 100 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

3-Methyl-GABA 1216629-00-3 Others 3 Methyl GABA 3MethylGABA inhibitor inhibit

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