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(±)-N-3-Benzylnirvanol

Name: (±)-N-3-Benzylnirvanol
Brand: TargetMol
SKU: T37332
Price: 51 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37332Cas No. 93879-40-4

(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-)-N-3-Benzylnirvanol. Both enantiomers are selective inhibitors of cytochrome P450, specifically inhibiting CYP2C19. (±)-N-3-Benzylnirvanol also reduces plasma cholesterol levels in mice.

(±)-N-3-Benzylnirvanol

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Purity: 98.31%

Catalog No. T37332Cas No. 93879-40-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$51	In Stock	In Stock
5 mg	$122	In Stock	In Stock
10 mg	$222	In Stock	In Stock
25 mg	$447	In Stock	In Stock
50 mg	$636	-	In Stock
100 mg	$886	-	In Stock
500 mg	$1,790	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.31%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-)-N-3-Benzylnirvanol. Both enantiomers are selective inhibitors of cytochrome P450, specifically inhibiting CYP2C19. (±)-N-3-Benzylnirvanol also reduces plasma cholesterol levels in mice.
Targets&IC50	CYP2C19:0.25 μM(ki)

Chemical Properties

Molecular Weight	294.35
Formula	C₁₈H₁₈N₂O₂
Cas No.	93879-40-4
Smiles	CCC1(NC(=O)N(Cc2ccccc2)C1=O)c1ccccc1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 225 mg/mL (764.4 mM), Sonication is recommended.

Methanol: Slightly soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3973 mL	16.9866 mL	33.9732 mL	169.8658 mL
5 mM	0.6795 mL	3.3973 mL	6.7946 mL	33.9732 mL
10 mM	0.3397 mL	1.6987 mL	3.3973 mL	16.9866 mL
20 mM	0.1699 mL	0.8493 mL	1.6987 mL	8.4933 mL
50 mM	0.0679 mL	0.3397 mL	0.6795 mL	3.3973 mL
100 mM	0.0340 mL	0.1699 mL	0.3397 mL	1.6987 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc