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(±)-N-3-Benzylnirvanol

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Catalog No. T37332Cas No. 93879-40-4

(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-)-N-3-Benzylnirvanol. Both enantiomers are selective inhibitors of cytochrome P450, specifically inhibiting CYP2C19. (±)-N-3-Benzylnirvanol also reduces plasma cholesterol levels in mice.

(±)-N-3-Benzylnirvanol
Other Forms of (±)-N-3-Benzylnirvanol:
(S)-(+)-N-3-BenzylnirvanolT67926790676-40-3
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(±)-N-3-Benzylnirvanol

🥰Excellent
Purity: 98.31%
Catalog No. T37332Cas No. 93879-40-4
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-)-N-3-Benzylnirvanol. Both enantiomers are selective inhibitors of cytochrome P450, specifically inhibiting CYP2C19. (±)-N-3-Benzylnirvanol also reduces plasma cholesterol levels in mice.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$51In StockIn Stock
5 mg$122In StockIn Stock
10 mg$222In StockIn Stock
25 mg$447In StockIn Stock
50 mg$636In StockIn Stock
100 mg$886-In Stock
500 mg$1,790-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.31%
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Product Introduction

Bioactivity
Description
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-)-N-3-Benzylnirvanol. Both enantiomers are selective inhibitors of cytochrome P450, specifically inhibiting CYP2C19. (±)-N-3-Benzylnirvanol also reduces plasma cholesterol levels in mice.
Targets&IC50
CYP2C19:0.25 μM(ki)
Chemical Properties
Molecular Weight294.35
FormulaC18H18N2O2
Cas No.93879-40-4
SmilesCCC1(NC(=O)N(Cc2ccccc2)C1=O)c1ccccc1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 225.0 mg/mL (764.4 mM), Sonication is recommended.
Methanol: Slightly soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3973 mL16.9866 mL33.9732 mL169.8658 mL
5 mM0.6795 mL3.3973 mL6.7946 mL33.9732 mL
10 mM0.3397 mL1.6987 mL3.3973 mL16.9866 mL
20 mM0.1699 mL0.8493 mL1.6987 mL8.4933 mL
50 mM0.0679 mL0.3397 mL0.6795 mL3.3973 mL
100 mM0.0340 mL0.1699 mL0.3397 mL1.6987 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-3-BenzylnirvanolCYP2C19(±)N3Benzylnirvanol(±) N 3 Benzylnirvanol
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