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CTLA-4 Protein, Cavia porcellus, Recombinant (His)

(Synonyms: Cytotoxic T-lymphocyte-associated antigen 4, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, CD152) Copy Product Info

Synonyms: Cytotoxic T-lymphocyte-associated antigen 4, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, CD152

Catalog No. TMPJ-00640 Copy Product Info
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 KDa and the accession number is H0VUB1.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$1167-10 days7-10 days
20 µg$1767-10 days7-10 days
50 µg$3107-10 days7-10 days
100 µg$4857-10 days7-10 days
200 µg$7627-10 days7-10 days
500 µg$1,3907-10 days7-10 days
1 mg$1,9807-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Mouse B7-1-Fc at 5 μg/ml (100 μl/well) can bind Cavia porcellus CTLA-4-His . The ED50 of Recombinant Cavia porcellus CTLA-4-His is 4.29 ng/ml. (Regularly tested)
Description
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 KDa and the accession number is H0VUB1.
Species
Cavia porcellus
Expression System
P. pastoris (Yeast)
TagC-6xHis
Accession NumberH0VUB1
Amino AcidAla37-Asp161
ConstructionAla37-Asp161
Protein Purity
Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of PBS, pH 7.4.
SynonymsCytotoxic T-lymphocyte-associated antigen 4, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, CD152
Research Background
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
Chemical Properties
Molecular Weight18-40 KDa (reducing condition)
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: CTLA-4 Protein, Cavia porcellus, Recombinant (His) chemical structure | CTLA-4 Protein, Cavia porcellus, Recombinant (His) molecular weight