Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), requiring ATP and Mg2+. It is further converted to thymidine 5′-triphosphate (dTTP) via TMPK catalysis. The activity of TMPK can be monitored by assessing the levels of dTDP [1] [2].
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Description | Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), requiring ATP and Mg2+. It is further converted to thymidine 5′-triphosphate (dTTP) via TMPK catalysis. The activity of TMPK can be monitored by assessing the levels of dTDP [1] [2]. |
Molecular Weight | 402.19 |
Formula | C10H16N2O11P2 |
CAS No. | 491-97-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thymidine 5′-diphosphate 491-97-4 inhibitor inhibit