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RS 61443

Catalog No. T0245 CAS 115007-34-6

Synonyms: RS61443, Mycophenolate mofetil, TM-MMF

RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)

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RS 61443, CAS 115007-34-6

Pack Size	Availability	Price/USD
25 mg	In stock	$ 31.00
50 mg	In stock	$ 44.00
100 mg	In stock	$ 63.00
200 mg	In stock	$ 97.00
500 mg	In stock	$ 165.00
1 g	In stock	$ 257.00
1 mL * 10 mM (in DMSO)	In stock	$ 68.00

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Purity: 99.9%

Purity: 99.37%

Purity: 99.26%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)

In vitro

Mycophenolate mofetil (MMF) is a relatively new systemic immunosuppressive agent whose use is rapidly increasing within the field of dermatologic. Originally used in the 1970s for the treatment of psoriasis, MMF has demonstrated efficacy in multiple types of inflammatory skin diseases. Although the safety data within the dermatologic literature is sparse, MMF's extensive use within the field of organ transplantation has demonstrated a favorable safety profile. MMF's lack of hepatic or renal toxicity is a significant advantage over immunosuppressive medications currently used in dermatology and make MMF an attractive candidate for multidrug regimens.

Synonyms	RS61443, Mycophenolate mofetil, TM-MMF
Molecular Weight	433.5
Formula	C23H31NO7
CAS No.	115007-34-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 11 mg/mL (25.37 mM)

References and Literature

1. Zwerner J , Fiorentino D . Mycophenolate mofetil[J]. Dermatologic Therapy, 2010, 20(4):229-238.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Drug Repurposing Compound Library NO PAINS Compound Library FDA-Approved Drug Library Anti-Cancer Metabolism Compound Library Bioactive Compounds Library Max FDA-Approved & Pharmacopeia Drug Library Human Metabolite Library Metabolism Compound Library Bioactive Compound Library

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Related compounds with same targets

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

RS 61443 115007-34-6 Metabolism Dehydrogenase RS61443 RS-61443 Mycophenolate mofetil TM-MMF inhibitor inhibit

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