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PARP14 inhibitor H10

Name: PARP14 inhibitor H10
Brand: TargetMol
SKU: T12366
Rating: 4.5 (1 reviews)

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Catalog No. T12366Cas No. 2084811-68-5

PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM

PARP14 inhibitor H10

😃Good

Catalog No. T12366Cas No. 2084811-68-5

PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$1,330	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
Targets&IC50	PARP1:, PARP14:490 nM

Chemical Properties

Molecular Weight	557.58
Formula	C₂₄H₂₇N₇O₇S
Cas No.	2084811-68-5
Relative Density.	1.50 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 62.5 mg/mL (112.09 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2.5 mg/mL (4.48 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7935 mL	8.9673 mL	17.9346 mL	89.6732 mL
5 mM	0.3587 mL	1.7935 mL	3.5869 mL	17.9346 mL
10 mM	0.1793 mL	0.8967 mL	1.7935 mL	8.9673 mL
20 mM	0.0897 mL	0.4484 mL	0.8967 mL	4.4837 mL
50 mM	0.0359 mL	0.1793 mL	0.3587 mL	1.7935 mL
100 mM	0.0179 mL	0.0897 mL	0.1793 mL	0.8967 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc