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Nigranoic acid

Catalog No. T13796   CAS 39111-07-4

Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.

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Nigranoic acid Chemical Structure
Nigranoic acid, CAS 39111-07-4
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.
In vivo Nigranoic acid has a strong protective effect on rat cerebral ischemia-reperfusion injury, and acts by downregulating nerve cell apoptosis by preventing the overactivation of PARP and AIF nuclear translocation[1].
Molecular Weight 470.68
Formula C30H46O4
CAS No. 39111-07-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Feng T, et al. Protective effects of nigranoic acid on cerebral ischemia-reperfusion injury and its mechanism involving apoptotic signaling pathway. Cell Biochem Biophys. 2015 Jan;71(1):345-51. 2. Sun HD, et al. Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase. J Nat Prod. 1996 May;59(5):525-7.

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Absinthin Schisantherin D AMD 3465 (S)-BI-1001 NNRTIs-IN-3 HIV-1 protease-IN-8 HIV-1 protease-IN-9 HIV-1 protease-IN-11

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Keywords

Nigranoic acid 39111-07-4 Microbiology/Virology Proteases/Proteasome HIV Protease inhibitor inhibit

 

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