Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues. NKY80 is a non-competitive inhibitor of adenylyl cyclase type V isoform (IC50s: 8.3 µM, 132 µM, and 1.7 mM for type V, III and II, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 62.00 | |
10 mg | In stock | $ 97.00 | |
25 mg | In stock | $ 197.00 | |
50 mg | In stock | $ 343.00 | |
100 mg | In stock | $ 523.00 | |
200 mg | In stock | $ 753.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 107.00 |
Description | NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues. NKY80 is a non-competitive inhibitor of adenylyl cyclase type V isoform (IC50s: 8.3 µM, 132 µM, and 1.7 mM for type V, III and II, respectively). |
Targets&IC50 | AC type III:132 μM, AC type V:8.3 μM, AC type II:1.7 mM |
In vitro | NKY80 (20 μM) blocks the increase in LVP and ventricular cAMP levels[2]. NKY80 (20 μM; 2 hours) completely blocks the elevations in both cAMP content and renin release from isolated JG cells[3]. |
Synonyms | Adenylyl cyclase type V Inhibitor |
Molecular Weight | 229.23 |
Formula | C12H11N3O2 |
CAS No. | 299442-43-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225 mg/mL (981.5 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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NKY80 299442-43-6 Neuroscience Adenylyl cyclase Adenylyl cyclase type V Inhibitor NKY 80 NKY-80 inhibitor inhibit