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N-(4-Carboxycyclohexylmethyl)maleimide

Catalog No. T16167 CAS 64987-82-2

N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker suitable for synthesizing PROTACs[1].

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N-(4-Carboxycyclohexylmethyl)maleimide Chemical Structure

N-(4-Carboxycyclohexylmethyl)maleimide, CAS 64987-82-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker suitable for synthesizing PROTACs[1].
In vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight	237.25
Formula	C12H15NO4
CAS No.	64987-82-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

N-(4-Carboxycyclohexylmethyl)maleimide 64987-82-2 Others N(4Carboxycyclohexylmethyl)maleimide N (4 Carboxycyclohexylmethyl)maleimide inhibitor inhibit

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