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Meseclazone

Catalog No. T16353   CAS 29053-27-8
Synonyms: W2395, NSC297623

Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.

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Meseclazone Chemical Structure
Meseclazone, CAS 29053-27-8
Pack Size Availability Price/USD Quantity
25 mg 6-8 weeks $ 1,520.00
50 mg 6-8 weeks $ 1,980.00
100 mg 6-8 weeks $ 2,500.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.
In vivo Intravenous administration of Meseclazone and other nonsteroidal anti-inflammatory drugs induced a dose-dependent inhibition of bronchoconstriction. This causing the following order of descending potency: isoproterenol congruent to indomethacin greater than fenoprofen greater than tolmetin greater than aspirin greater than naproxen congruent to ibuprofen greater than phenylbutazone greater than diflunisal greater than Meseclazone greater than 5-CSA. Meseclazone inhibits collagen-induced aggregation 1 and 4 hr after oral administration[1][2].
Synonyms W2395, NSC297623
Molecular Weight 239.65
Formula C11H10ClNO3
CAS No. 29053-27-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Diamantis W, et al. Meseclazone, 5-chlorosalicylic acid and acetylsalicylic acid. Comparison of their effects on in vitro and ex vivo platelet aggregation. Thromb Haemost. 1978 Aug 31;40(1):24-36. 2. Diamantis W, et al. Antagonism by meseclazone and other nonsteroidal anti-inflammatory drugs of bradykinin-induced bronchospasm. Pharmacology. 1982;24(4):243-7.

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Keywords

Meseclazone 29053-27-8 Neuroscience AChR W2395 W 2395 W-2395 NSC-297623 NSC297623 NSC 297623 inhibitor inhibit

 

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