Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 113.00 | |
10 mg | In stock | $ 172.00 | |
25 mg | In stock | $ 322.00 | |
50 mg | In stock | $ 428.00 | |
100 mg | In stock | $ 572.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 125.00 |
Description | MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM). |
Targets&IC50 | MPI:1 μM (IC50) |
In vitro | MLS0315771 is toxic to the zebrafish embryos above 2 μM. MLS0315771 toxicity at higher concentrations is an off-target effect. MLS0315771 enhances mannose flux toward glycosylation. It ~50% of embryos appeared sick within 20 min at 8-10 μM, and most of them die by 30-60 min. |
Molecular Weight | 273.33 |
Formula | C15H12FNOS |
CAS No. | 727664-91-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (40.24 mM)
You can also refer to dose conversion for different animals. More
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MLS0315771 727664-91-7 Others MLS-0315771 Inhibitor inhibit MLS 0315771 inhibitor