Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability in in vitro and in vivo assays and has a favorable overall ADME profile.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 380.00 | |
5 mg | In stock | $ 890.00 | |
10 mg | In stock | $ 1,230.00 | |
25 mg | In stock | $ 1,830.00 | |
50 mg | In stock | $ 2,480.00 | |
100 mg | In stock | $ 3,350.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 1,590.00 |
Description | MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability in in vitro and in vivo assays and has a favorable overall ADME profile. |
In vitro | MK-8325 (7 μM) demonstrates no cell toxicity with a CC50 > 25 mM against Huh-7 replicon cells in a standard MTS assay.[1] |
In vivo | In vivo assays showed MK-8325 to be orally bioavailable with pharmacokinetics suitable for once-daily dosing in patients and good overall ADME profiles.[1] |
Synonyms | MK 8325, MK8325 |
Molecular Weight | 915.93 |
Formula | C43H54Cl2F2N8O6Si |
CAS No. | 1334314-19-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9.16 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MK-8325 1334314-19-0 Microbiology/Virology Proteases/Proteasome HCV Protease MK 8325 MK8325 inhibitor inhibit