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Lexipafant

Catalog No. T27821   CAS 139133-26-9
Synonyms: ISV-611, GR-167089, DO-6, BB-882, DO6, BB882

Lexipafant is a platelet-activating factor (PAF) receptor antagonist.

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Lexipafant Chemical Structure
Lexipafant, CAS 139133-26-9
Pack Size Availability Price/USD Quantity
5 mg 6-8 weeks
$ 1,070.00
$ 856.00
50 mg 6-8 weeks
$ 2,180.00
$ 1,744.00
100 mg 6-8 weeks
$ 2,800.00
$ 2,240.00
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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Lexipafant is a platelet-activating factor (PAF) receptor antagonist.
Synonyms ISV-611, GR-167089, DO-6, BB-882, DO6, BB882
Molecular Weight 458.57
Formula C23H30N4O4S
CAS No. 139133-26-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Oztürk H, Oztürk H, Dokucu AI, Otcu S. Effects of lexipafant (BB-882), a platelet activating factor receptor antagonist, on liver damage due to bile duct ligation in rats. Acta Gastroenterol Belg. 2006 Apr-Jun;69(2):197-202. PubMed PMID: 16929615. 2. Aldemir M, Boşnak M, Al B, Büyükbayram H, Taçyildiz I. Effects of molsidomine and lexipafant in hepatic ischaemia--reperfusion injury. Injury. 2004 Mar;35(3):232-7. PubMed PMID: 15124788. 3. Johnson CD, Kingsnorth AN, Imrie CW, McMahon MJ, Neoptolemos JP, McKay C, Toh SK, Skaife P, Leeder PC, Wilson P, Larvin M, Curtis LD. Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis. Gut. 2001 Jan;48(1):62-9. PubMed PMID: 11115824; PubMed Central PMCID: PMC1728186. 4. Börjesson A, Wang X, Sun Z, Inghammar M, Truedsson L, Andersson R. Early treatment with lexipafant, a platelet-activating factor-receptor antagonist, is not sufficient to prevent pulmonary endothelial damage after intestinal ischaemia and reperfusion in rats. Dig Liver Dis. 2002 Mar;34(3):190-6. PubMed PMID: 11990391.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lexipafant 139133-26-9 ISV-611 GR 167089 GR-167089 ISV611 ISV 611 BB 882 DO-6 BB-882 GR167089 DO 6 DO6 BB882 inhibitor inhibit

 

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