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Kalii Dehydrographolidi Succinas

Catalog No. T3667 CAS 76958-99-1

Synonyms: Ddhads, Dehydroandrographolide Succinate Potasium Salt

Dehydroandrographolide Succinate Potasium Salt is a natural compound with anti-virus infection activity.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Kalii Dehydrographolidi Succinas, CAS 76958-99-1

Pack Size	Availability	Price/USD
5 mg	In stock	$ 38.00
10 mg	In stock	$ 52.00
25 mg	In stock	$ 93.00
50 mg	In stock	$ 132.00
100 mg	In stock	$ 177.00
200 mg	In stock	$ 259.00
500 mg	In stock	$ 438.00
1 mL * 10 mM (in DMSO)	In stock	$ 51.00

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Purity: 97.42%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Dehydroandrographolide Succinate Potasium Salt is a natural compound with anti-virus infection activity.

Kinase Assay

In vitro kinase assay is based on a filter binding assay, using the recombinant GST-fused kinase domains expressed in baculovirus and purified over glutathione-sepharose, γ-[33P]ATP as the phosphate donor, and poly(Glu:Tyr 4:1) peptide as the acceptor. Each GST-fused kinase is incubated under optimized buffer conditions [20 mM Tris-HCl buffer (pH 7.5), 1-3 mM MnCl2, 3-10 mM MgCl2, 3-8 μg/mL poly(Glu:Tyr 4:1), 0.25 mg/mL polyethylene glycol 20000, 8 μM ATP, 10 μM sodium vanadate, 1 mM DTT] and 0.2 μCi γ-33P ATP in a total volume of 30 μL in the presence or absence of a test substance for 10 min at ambient temperature. The reaction is stopped by adding 10 mL of 250 mM EDTA. Using a 384-well filter system, half the volume is transferred onto an Immobilon-polyvinylidene difluoride membrane. The membrane is then washed extensively and dried, and scintillation counting is performed. IC50s for compounds are calculated by linear regression analysis of the percentage inhibition[1].

Synonyms	Ddhads, Dehydroandrographolide Succinate Potasium Salt
Molecular Weight	570.67
Formula	C28H35OK10
CAS No.	76958-99-1

Storage

keep away from direct sunlight,store under nitrogen

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mg/mL(17.5 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Hsieh MJ, et al. Oncotarget. 2015 Oct 13;6(31):30831-49.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compounds Library Max Traditional Chinese Medicine Monomer Library FDA-Approved & Pharmacopeia Drug Library Anti-Tumor Natural Product Library Anti-infective Natural Product Library NMPA-Approved Drug Library Natural Product Library Natural Product Library for HTS Approved Drug Library Anti-Viral Compound Library

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

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Step Two: Enter the in vivo formulation

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Kalii Dehydrographolidi Succinas 76958-99-1 Others Ddhads inhibit Dehydroandrographolide Succinate Potasium Salt Potassium dehydroandrographolide Inhibitor inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.