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Kalii Dehydrographolidi Succinas

Catalog No. T3667 CAS 76958-99-1

Synonyms: Ddhads, Dehydroandrographolide Succinate Potasium Salt

Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Kalii Dehydrographolidi Succinas Chemical Structure

Kalii Dehydrographolidi Succinas, CAS 76958-99-1

Pack Size	Availability	Price/USD
5 mg	In stock	$ 38.00
10 mg	In stock	$ 52.00
25 mg	In stock	$ 93.00
50 mg	In stock	$ 132.00
100 mg	In stock	$ 177.00
200 mg	In stock	$ 259.00
500 mg	In stock	$ 438.00
1 g	In stock	$ 647.00
1 mL * 10 mM (in DMSO)	In stock	$ 51.00

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Purity: 97.42%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity.

Kinase Assay

In vitro kinase assay is based on a filter binding assay, using the recombinant GST-fused kinase domains expressed in baculovirus and purified over glutathione-sepharose, γ-[33P]ATP as the phosphate donor, and poly(Glu:Tyr 4:1) peptide as the acceptor. Each GST-fused kinase is incubated under optimized buffer conditions [20 mM Tris-HCl buffer (pH 7.5), 1-3 mM MnCl2, 3-10 mM MgCl2, 3-8 μg/mL poly(Glu:Tyr 4:1), 0.25 mg/mL polyethylene glycol 20000, 8 μM ATP, 10 μM sodium vanadate, 1 mM DTT] and 0.2 μCi γ-33P ATP in a total volume of 30 μL in the presence or absence of a test substance for 10 min at ambient temperature. The reaction is stopped by adding 10 mL of 250 mM EDTA. Using a 384-well filter system, half the volume is transferred onto an Immobilon-polyvinylidene difluoride membrane. The membrane is then washed extensively and dried, and scintillation counting is performed. IC50s for compounds are calculated by linear regression analysis of the percentage inhibition[1].

Synonyms	Ddhads, Dehydroandrographolide Succinate Potasium Salt
Molecular Weight	570.67
Formula	C28H35KO10
CAS No.	76958-99-1

Storage

keep away from direct sunlight,store under nitrogen

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL(17.5 mM)

References and Literature

1. Hsieh MJ, et al. Oncotarget. 2015 Oct 13;6(31):30831-49.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library Drug Repurposing Compound Library Anti-virus Traditional Chinese Medicine Monomer Library Anti-Viral Compound Library Bioactive Compounds Library Max Approved Drug Library Natural Product Library Selected Plant-Sourced Compound Library Anti-Tumor Natural Product Library Natural Product Library for HTS

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Kalii Dehydrographolidi Succinas 76958-99-1 Others Ddhads inhibit Potassium dehydroandrographolide Inhibitor Dehydroandrographolide Succinate Potasium Salt inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.