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Glabranine

Catalog No. TN1689 CAS 41983-91-9

Synonyms: Glabranin

Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. Glabranin or a derivative thereof could be used to stimulate hair growth. Glabranine exerts a dose-dependent inhibitory effect in vitro on the dengue virus, it presents 70% inhibition on the dengue virus at a concentration of 25 microM.

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Glabranine, CAS 41983-91-9

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Description	Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. Glabranin or a derivative thereof could be used to stimulate hair growth. Glabranine exerts a dose-dependent inhibitory effect in vitro on the dengue virus, it presents 70% inhibition on the dengue virus at a concentration of 25 microM.
In vitro	The ethyl acetate and methanol bark extracts of Melicope glabra were evaluated for their antioxidant capacities by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and β-carotene bleaching/linoleic acid system. Both extracts exhibited strong inhibition against the DPPH radical (IC50 values of 24.81 and 13.01 μg ml(-1), respectively) and strong antioxidant activity in β-carotene bleaching assay. Both samples were found to have high phenolic content with values of 39 and 44 mg GAE/g as indicated by Follin-Ciocalteau's reagent. Antioxidant TLC assay-guided isolation on the methanol extract led to the isolation of a new pyranocoumarin, Glabranin (1), umbelliferone (2), scopoletin (3) and sesamin (4), and their structures were determined by spectroscopy[1]
Source	Natural Products > Fabaceae > Glycyrrhiza

Synonyms	Glabranin
Molecular Weight	324.37
Formula	C20H20O4
CAS No.	41983-91-9

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Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Antioxidant activity-guided separation of coumarins and lignan from Melicope glabra (Rutaceae).Food Chem. 2013 Aug 15;139(1-4):87-92.

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Keywords

Glabranine 41983-91-9 Microbiology/Virology Antifection Glabranin inhibitor inhibit

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