Powder: -20°C for 3 years | In solvent: -80°C for 2 years
Galantide is a reversible and non-specific antagonist of galanin receptor.
Pack Size | Availability | Price/USD | Quantity |
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10 mg | Inquiry | $ 995.00 |
Description | Galantide is a reversible and non-specific antagonist of galanin receptor. |
In vitro | Galantide is also found to displace 125I-monoiodo-[TyrZ6]galanin from membranes of the insulin-producing Rin m 5F cells (IC50: <0.1 nM). Galantide dose-dependently (IC50: 1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets [1]. |
In vivo | Galantide ameliorates mild acute pancreatitis (AP). Galantide has been found to improve social memory in 'social recognition' test when i.c.v. administered at doses varying from 6-6000 nM[4]. Galantide significantly reduces AP-induced hyperenzymemia by 41–49% [3]. Galanin (5 μg/rat; intracerebroventricular injection ) inhibited sexual behavior in experienced male rats--without producing any other locomotor or behavioral deficit-, injection of the galanin antagonist, galantide, by the same route (1 or 2 μg/rat) stimulated sexual behavior (improving arousal, motivation and performance indexes) and antagonized the effect of galanin [2]. |
Molecular Weight | 2199.53 |
Formula | C104H151N25O26S |
CAS No. | 138579-66-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Galantide 138579-66-5 Others inhibitor inhibit