Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | 35 days | $ 788.00 |
Description | Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. |
Targets&IC50 | KSP:6 nM (IC50) |
Synonyms | Filanesib trifluoroacetic acid, ARRY-520 TFA, ARRY 520 TFA, ARRY520 TFA |
Molecular Weight | 534.5 |
Formula | C22H23F5N4O4S |
CAS No. | 1781834-99-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Filanesib TFA 1781834-99-8 Filanesib trifluoroacetic acid ARRY-520 TFA ARRY 520 TFA ARRY520 TFA inhibitor inhibit