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Enterostatin (human,mouse,rat)

Name: Enterostatin (human,mouse,rat)
Brand: TargetMol
SKU: TP1835
Price: 63 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TP1835 Copy Product Info

Purity: 99.78%

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Enterostatin (human,mouse,rat) is a pentapeptide (Val-Pro-Asp-Pro-Arg) generated by cleavage of the pro-pancreatic lipase precursor, involved in regulating fat intake and energy metabolism. Enterostatin (human, mouse, rat) affects appetite and lipid utilization through central and peripheral mechanisms and is commonly used in metabolic and obesity-related research.

Cas No. 117830-79-2

Pack Size	Price	USA Stock	Global Stock	Quantity
1 mg	$63	-	In Stock
5 mg	$148	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.78%

Appearance:Solid

Color:White

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COA LCMS

Product Introduction

Bioactivity

Description

In vivo

Enterostatin (human,mouse,rat) （100 mM）, in the perfused ratpancreas, inhibits the insulin response to 9 mM glucose (by 70%), 0.1 mM tolbutamide (by 40%), and 5 mM arginine (by 70%)[1].
Enterostatin (human,mouse,rat) enhances memory consolidation after central or oral administration at a dose of 10 nmol/mouse or 300 mg/kg, respectively, in a step-through type passive avoidance test in mice[3].
A dose of 38 nmol of Enterostatin (human,mouse,rat) gives a significant inhibition of high-fat food intake, while at a higher dose of 76 nmol the inhibiting effect is lost. During the first hour, after injection of enterostatin, there is even a slight increase in food intake[4].

Chemical Properties

Molecular Weight	496.57
Formula	C₂₁H₃₆N₈O₆
Cas No.	117830-79-2
Smiles	C(N[C@@H](CCCNC(=N)N)C(O)=O)(=O)[C@H]1N(C(CNC(=O)[C@H]2N(C([C@H](C)N)=O)CCC2)=O)CCC1
Relative Density.	1.54g/cm3
Sequence	Ala-Pro-Gly-Pro-Arg
Sequence Short	APGPR

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (201.38 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0138 mL	10.0691 mL	20.1381 mL	100.6907 mL
5 mM	0.4028 mL	2.0138 mL	4.0276 mL	20.1381 mL
10 mM	0.2014 mL	1.0069 mL	2.0138 mL	10.0691 mL
20 mM	0.1007 mL	0.5035 mL	1.0069 mL	5.0345 mL
50 mM	0.0403 mL	0.2014 mL	0.4028 mL	2.0138 mL
100 mM	0.0201 mL	0.1007 mL	0.2014 mL	1.0069 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Enterostatin, human, mouse, ratEnterostatin(human,mouse,rat)Enterostatin

Related Tags: Enterostatin (human,mouse,rat) chemical structure | Enterostatin (human,mouse,rat) in vivo | Enterostatin (human,mouse,rat) formula | Enterostatin (human,mouse,rat) molecular weight