Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 6-8 weeks | $ 446.00 | |
25 mg | 6-8 weeks | $ 1,430.00 | |
50 mg | 6-8 weeks | $ 1,860.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM). |
Targets&IC50 | ALDH3A1:2 uM |
In vitro | EN40 (10-1000 μM; 48 hours) displays an inhibitory effect on ALDH3A1 activity. It also impairs A549 cell survival. |
In vivo | EN40 (i.p.; 50mg/kg; from 14 days; once per day) displays strong anti-tumorigenic effects in established A549 tumor xenografts and it also shows good tolerability with no bodyweight loss in mice. |
Molecular Weight | 217.26 |
Formula | C13H15NO2 |
CAS No. | 2094547-67-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL (23.01 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
EN40 2094547-67-6 Others EN 40 EN-40 inhibitor inhibit