Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg/mL).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
5 mg | In stock | $ 372.00 | |
10 mg | In stock | $ 556.00 | |
25 mg | In stock | $ 896.00 | |
50 mg | In stock | $ 1,220.00 | |
100 mg | In stock | $ 1,650.00 |
Description | Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg/mL). |
Targets&IC50 | MRSA:2 μg/mL (MIC90) |
In vitro | Ceftobiprole has demonstrated activity against important gram-positive bacteria, including penicillin-resistant S. pneumonia (PRSP), Methicillin-resistant S. aureus (MRSA), and E. faecalis (MIC90 values of 0.25, 2, and 2 mcg/mL). Ceftobiprole has also demonstrated potent in vitro activity against several clinical isolates of community-associated Methicillin-resistant S. aureus (CA-MRSA), vancomycin-intermediate S. aureus (VISA), and Vancomycin-resistant S. aureus (VRSA), with a minimum inhibitory concentration (MIC) of 2 mcg/mL [1]. Ceftobiprole is highly active against S. aureus, with MICs ranging from 0.12 to 4 mg/L (only one resistant strain, MIC of 4 mg/L). Furthermore, Ceftobiprole is twice more active on Methicillin-susceptible S. aureus (MSSA) strains with MIC50 and MIC90 of 0.5 mg/L than on MRSA strains with MIC50 and MIC90 of 1 mg/L. Moreover, Panton-Valentine leukocidin (PVL)+MRSA is slightly more susceptible to Ceftobiprole (MIC50: 0.5 mg/L, MIC90: 1 mg/L) than PVL-MRSA (MIC50 and MIC90 of 1 mg/L) [2]. |
Synonyms | Ro 63-9141, BAL 9141 |
Molecular Weight | 534.57 |
Formula | C20H22N8O6S2 |
CAS No. | 209467-52-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL (9.35 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Ceftobiprole 209467-52-7 Microbiology/Virology Antibacterial cephalosporin BAL9141 inhibit vancomycin penicillin staphylococci Ro 63-9141 Bacterial pyrrolidinone BAL-9141 pathogens gram-positive BAL 9141 VRSA gram-negative Inhibitor MRSA methicillin inhibitor