Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calmodulin-binding IQ motif of PEP-19.
Description | Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calmodulin-binding IQ motif of PEP-19. |
In vitro | A truncated Camstatin acetate-in which the IQ motif serine is the only phosphorylatable residue-was screened against 42 different kinases. Truncated Camstatin acetate is selectively phosphorylated by four isoforms of protein kinase C. Treatment of full-length PEP-19 with PKCgamma catalyzes phosphorylation of the same serine residue. Phosphorylation of Camstatin acetate inhibits its binding to calmodulin. Both Camstatin acetate and phospho-Camstatin acetate exist in similar dynamic turn-like conformations[1]. |
Molecular Weight | 2820.21 |
Formula | C124H207N39O36 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Camstatin acetate 免疫与炎症 NO Synthase Inhibitor inhibitor inhibit