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Camstatin acetate
🥰Excellent
Catalog No. TP2057L
Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calmodulin-binding IQ motif of PEP-19.
Camstatin acetate
🥰Excellent
Purity: 98.30%
Catalog No. TP2057L
Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calmodulin-binding IQ motif of PEP-19.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $89 | In Stock | |
| 5 mg | $202 | In Stock | |
| 10 mg | $298 | In Stock | |
| 25 mg | $476 | In Stock | |
| 50 mg | $678 | In Stock | |
| 100 mg | $912 | In Stock | |
| 200 mg | $1,220 | In Stock |
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CitedSelect Batch
Purity:98.30%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calmodulin-binding IQ motif of PEP-19. |
| In vitro | A truncated Camstatin acetate-in which the IQ motif serine is the only phosphorylatable residue-was screened against 42 different kinases. Truncated Camstatin acetate is selectively phosphorylated by four isoforms of protein kinase C. Treatment of full-length PEP-19 with PKCgamma catalyzes phosphorylation of the same serine residue. Phosphorylation of Camstatin acetate inhibits its binding to calmodulin. Both Camstatin acetate and phospho-Camstatin acetate exist in similar dynamic turn-like conformations[1]. |
| Molecular Weight | 2820.21 |
| Formula | C124H207N39O36 |
| Smiles | CC(O)=O.OC[C@@H](C(N)=O)NC(CNC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@H](CC1=CC=CC=C1)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@H]3N(C([C@H](C)N)=O)CCC3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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