Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor targeting calpain I (μ-calpain) with a Ki value of 19 nM. It exhibits lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). This compound is potentially useful for investigating calpains' involvement in various processes such as neutrophil chemotaxis, neuronal signaling, and cardiac responses to injury [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 253.00 | |
5 mg | 35 days | $ 1,120.00 | |
10 mg | 35 days | $ 1,860.00 |
Description | (Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor targeting calpain I (μ-calpain) with a Ki value of 19 nM. It exhibits lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). This compound is potentially useful for investigating calpains' involvement in various processes such as neutrophil chemotaxis, neuronal signaling, and cardiac responses to injury [1]. |
Molecular Weight | 482.57 |
Formula | C26H34N4O5 |
CAS No. | 181769-57-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Calpain Inhibitor XII 181769-57-3 inhibitor inhibit