Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with targeted agents or standard chemotherapy.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with targeted agents or standard chemotherapy. |
Targets&IC50 | KDM5A:10 nM |
Molecular Weight | 314.77 |
Formula | C16H15ClN4O |
CAS No. | 2095432-28-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CPI-455 HCl 2095432-28-1 Chromatin/Epigenetic Histone Demethylase CPI455 HCl CPI 455 HCl inhibitor inhibit