Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aminoethyl-SS-ethylalcohol (Compound 3) is an Alkyl-Chain-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
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Description | Aminoethyl-SS-ethylalcohol (Compound 3) is an Alkyl-Chain-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2]. |
Molecular Weight | 153.27 |
Formula | C4H11NOS2 |
CAS No. | 15579-01-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Aminoethyl-SS-ethylalcohol 15579-01-8 Others Aminoethyl SS ethylalcohol AminoethylSSethylalcohol inhibitor inhibit