Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Amino-PEG27-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | Amino-PEG27-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | H2N-PEG27-CH2CH2NH2 |
Molecular Weight | 1249.52 |
Formula | C56H116N2O27 |
CAS No. | 2252208-09-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Amino-PEG27-amine 2252208-09-4 Others H2N-PEG27-CH2CH2NH2 AminoPEG27amine Amino-PEG-27-amine Amino PEG27 amine inhibitor inhibit