sodium hydrate

Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

Tolmetin sodium dihydrate, a non-steroidal anti-inflammatory drug (NSAID), is a potent and orally active inhibitor of COX (cyclooxygenase). Its IC 50 values for human COX-1 and COX-2 are 0.35 μM and 0.82 μM, respectively [1] [2].

UDP-α-D-Glucose is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It has been shown to bind the P2Y14receptor (EC50= 0.35 μM), an atypical P2Y receptor involved in the activation of dendritic cells and glial cells.1It can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.2 1.Jacobson, K.A., Ivanov, A.A., de Castro, S., et al.Development of selective agonists and antagonists of P2Y receptorsPurinergic Signal.5(1)75-89(2009) 2.Lecca, D., Trincavelli, M.L., Gelosa, P., et al.The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repairPLoS One3(10)(2008)

Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.

Amfenac Sodium Hydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety.

Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. Upon ophthalmic administration, bromfenac binds to and inhibits cyclooxygenase II (COX II), an enzyme that converts arachidonic acid to cyclic endoperoxides, which are prostaglandin (PG) precursors. By inhibiting PG formation, bromfenac prevents PG-induced inflammation, vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, increased vascular permeability, and elevated intraocular pressure (IOP).

Cholic acid sodium hydrate is a natural and orally active bile acid that is synthesized primarily by the liver and secreted into the bile, where it plays an important role in the digestive process, aiding in the absorption of fats by emulsifying them, as well as participating in the excretion of cholesterol and regulating the metabolism of bile acids.

Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX). Target: COX Dipyrone is a potent analgesic and antipyretic drug that has been used clinically for more than 80 years.

Meclofenamate sodium is a potent non-steroidal anti-inflammatory agent, which can specifically inhibit chemokine-induced human polymorphonuclear leukocyte function: chemotaxis, degranulation, and superoxide anion free radical production.

Dicloxacillin Sodium hydrate is a narrow-spectrum β-Lactam antibiotic of the penicillin class, used to treat infections caused by susceptible Gram-positive bacteria.

Saccharin, sodium salt hydrate is used in the food industry and for sweetening diabetes diet. It is also used as a synthetic sweet ignorance agent. Saccharin, sodium salt hydrate is the first generation′ synthetic sugar alternative that has been studied f

Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX1 2 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries, and may be used in studies of increased intracranial pressure secondary to severe traumatic brain injury and rheumatoid arthritis in adults.

Prasterone is an endogenous steroid hormone. Prasterone acts as an agonist at ERβ, NMDA, and σ1 receptors, a partial agonist at ERα and AR, and antagonist at GABA-A receptors. It displays a variety of biologocial activities, including enhancing working me

α-D-Glucose-1-phosphate sodium hydrate (Glucose-1-phosphate sodium hydrate) is an intermediate in glycogen metabolism and a precursor in UDP-glucose biosynthesis.

Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.

Estrone-3-Glucuronide sodium hydrate is the major metabolite of estrone, serving as a biological marker for sex determination in the Chinese giant salamander.

Avibactam sodium hydrate (NXL-104 hydrate) is a highly effective β-lactamase inhibitor that inhibits β-lactamases TEM-1 and CTX-M-15, as well as the carbapenemase produced by Klebsiella pneumoniae and carbapenem-resistant Enterobacteriaceae.

Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities. It can be used to study hypothyroidism, stroke and cognitive dysfunction.

Palmoxirate sodium hydrate is a potent inhibitor of long-chain fatty acid oxidation.

Cromoglicic acid , cromolyn (USAN), cromoglycate (former BAN), or cromoglicate, is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma. Cromoglicic acid requires administration four times daily, and does not provide additive benefit in combination with inhaled corticosteroids.

Alisertib sodium hydrate is a salt of Alisertib --- an inhibitor of Aurora A kinase with potential antineoplastic activity. Alisertib binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.

Methicillin sodium hydrate, a narrow-spectrum β-lactam antibiotic, inhibits penicillin-binding proteins (PBPs), targeting Staphylococcus aureus and Staphylococcus epidermidis resistant to other penicillins. It is utilized in researching skin infections, osteomyelitis, and endocarditis [1].

Deoxythymidine-5'-triphosphate (dTTP) sodium hydrate, a critical nucleoside triphosphate among the four, functions as a trisodium salt in DNA synthesis [1].

L-Tartaric acid (L-(+)-Tartaric acid) sodium hydrate, an enantiomer of D-tartaric acid, is a white crystalline dicarboxylic acid found in plants like grapes and is a primary organic acid in wine. This compound functions as a flour bulking agent and food additive, interacting with sodium bicarbonate to generate carbon dioxide [1].