Powder: -20°C for 3 years
In solvent: -80°C for 2 years
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor (CRLR) (IC50s: 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells).
Description | β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor (CRLR) (IC50s: 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells). |
Targets&IC50 | CRLR/RAMP1, cell assay:1 nM , CRLR/RAMP2, cell assay:300 nM |
In vitro | β-CGRP, human acts via a complex of the CRLR and RAMP, with IC50s of 1 nM in both SK-N-MC and Swiss 3T3 cells express CRLR and RAMP1, and 300 nM and 130 nM in HEK293T and NG108-15 cells expressing CRLR and RAMP2 [1]. CGRP is a potent vasodilator and also exhibits pro- and -anti-inflammatory activity [2]. |
Synonyms | CGRP-II (Human) (acetate), β-CGRP, human acetate (101462-82-2 free), Human β-CGRP acetate |
Molecular Weight | 3853.46 |
Formula | C164H271N51O50S3 |
CAS No. | TP2167 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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β-CGRP, human acetate TP2167 离子通道 CGRP Receptor Human β-CGRP acetate βCGRP, human acetate β CGRP, human acetate CGRP-II (Human) (acetate) β-CGRP, human acetate (101462-82-2 free) Inhibitor inhibitor inhibit