Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

PROTAC ERα Degrader-1

PROTAC ERα Degrader-1
PROTAC ERα Degrader-1 is a chemical compound. It consists of a ubiquitin E3 ligase binding group, a linker, and a protein binding group. This compound serves as a degrader of estrogen receptor-alpha (ERα).
Catalog No. T18636

Resource Download

PROTAC ERα Degrader-1

Catalog No. T18636

PROTAC ERα Degrader-1 is a chemical compound. It consists of a ubiquitin E3 ligase binding group, a linker, and a protein binding group. This compound serves as a degrader of estrogen receptor-alpha (ERα).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
100 mgInquiryBackorder
500 mgInquiryBackorder
Bulk & Custom
Add to Cart
Questions
View More

Product Introduction

Bioactivity
Description
PROTAC ERα Degrader-1 is a chemical compound. It consists of a ubiquitin E3 ligase binding group, a linker, and a protein binding group. This compound serves as a degrader of estrogen receptor-alpha (ERα).
In vitro
Treatment of HER2-expressing cells with PROTAC ERα Degrader-1 (without Ab; compound P1) leads to reduced estrogen receptor-alpha (ERα) levels[1].
Chemical Properties
Molecular Weight1120.29
FormulaC66H69N7O10
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 200 mg/mL (178.53 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.8926 mL4.4631 mL8.9263 mL44.6313 mL
5 mM0.1785 mL0.8926 mL1.7853 mL8.9263 mL
10 mM0.0893 mL0.4463 mL0.8926 mL4.4631 mL
20 mM0.0446 mL0.2232 mL0.4463 mL2.2316 mL
50 mM0.0179 mL0.0893 mL0.1785 mL0.8926 mL
100 mM0.0089 mL0.0446 mL0.0893 mL0.4463 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy PROTAC ERα Degrader-1 | purchase PROTAC ERα Degrader-1 | PROTAC ERα Degrader-1 cost | order PROTAC ERα Degrader-1 | PROTAC ERα Degrader-1 chemical structure | PROTAC ERα Degrader-1 in vitro | PROTAC ERα Degrader-1 formula | PROTAC ERα Degrader-1 molecular weight