Powder: -20°C for 3 years | In solvent: -80°C for 1 year
m-PEG10-acid is a non-cleavable 10-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker [1]. Furthermore, m-PEG10-acid serves as a PEG-based linker for the synthesis of proteolysis-targeting chimeras (PROTACs) [2].
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Description | m-PEG10-acid is a non-cleavable 10-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker [1]. Furthermore, m-PEG10-acid serves as a PEG-based linker for the synthesis of proteolysis-targeting chimeras (PROTACs) [2]. |
In vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 500.58 |
Formula | C22H44O12 |
CAS No. | 2409969-94-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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m-PEG10-acid 2409969-94-2 Others m PEG10 acid mPEG10acid m-PEG-10-acid inhibitor inhibit