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EGFR-IN-155

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Catalog No. T206383

EGFR-IN-155 (compound 13a) is an EGFR inhibitor with IC50 values of 0.14 nM for EGFRTK and 0.18 nM for EGFRL858R. EGFR-IN-155 suppresses tumor growth, causes cell cycle arrest at the S phase, and induces apoptosis (cell death).

EGFR-IN-155

EGFR-IN-155

😃Good
Catalog No. T206383
EGFR-IN-155 (compound 13a) is an EGFR inhibitor with IC50 values of 0.14 nM for EGFRTK and 0.18 nM for EGFRL858R. EGFR-IN-155 suppresses tumor growth, causes cell cycle arrest at the S phase, and induces apoptosis (cell death).
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
EGFR-IN-155 (compound 13a) is an EGFR inhibitor with IC50 values of 0.14 nM for EGFRTK and 0.18 nM for EGFRL858R. EGFR-IN-155 suppresses tumor growth, causes cell cycle arrest at the S phase, and induces apoptosis (cell death).
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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