Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aβ-IN-5 (Compound e12) is an orally active Aβ aggregation inhibitor that also inhibits AChE and BuChE with IC50 values of 21.29 μM and 1.32 μM, respectively. Furthermore, Aβ-IN-5 exhibits remarkable neuroprotective effects along with low neurotoxicity [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Aβ-IN-5 (Compound e12) is an orally active Aβ aggregation inhibitor that also inhibits AChE and BuChE with IC50 values of 21.29 μM and 1.32 μM, respectively. Furthermore, Aβ-IN-5 exhibits remarkable neuroprotective effects along with low neurotoxicity [1]. |
In vitro | Compound Aβ-IN-5 (e12) at a concentration of 25 μM significantly inhibits the aggregation of Aβ, achieving an inhibition rate of 72% [1]. |
In vivo | Compound Aβ-IN-5 (also known as Compound e12) administrated orally at a dosage of 15 mg/kg, enhances learning and memory functions without showing any signs of acute toxicity in vivo. |
Molecular Weight | 348.4 |
Formula | C21H20N2O3 |
CAS No. | 2417977-65-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Aβ-IN-5 2417977-65-0 inhibitor inhibit