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VPC 23019

Catalog No. T17237 CAS 449173-19-7

VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively). It is also an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).

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VPC 23019, CAS 449173-19-7

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 664.00
50 mg	6-8 weeks	$ 863.00
100 mg	6-8 weeks	$ 1,290.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description	VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively). It is also an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).
Targets&IC50	S1P1:(pEC50)6.58 , S1P1:(pki)7.86 , S1P3:5.93(pki), S1P3:7.07

Molecular Weight	372.4
Formula	C17H29N2O5P
CAS No.	449173-19-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Davis MD, et al. Sphingosine 1-phosphate analogs as receptor antagonists. J Biol Chem. 2005 Mar 18;280(11):9833-41. Epub 2004 Dec 8.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

VPC 23019 449173-19-7 GPCR/G Protein LPL Receptor S1P Receptor VPC23019 inhibit VPC-23019 Lysophospholipid Receptor Inhibitor inhibitor

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