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Tuna AI acetate

Catalog No. T24906L

Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.

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Tuna AI acetate, CAS N/A

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
Targets&IC50	hippuryl-L-histidyl-L-leucine:1.7 μM(rabbit lung ACE), angiotensin I:5.7 μM(rabbit lung ACE)
In vitro	Tuna AI acetate inhibited rabbit lung ACE non-competitively with Ki values of 1.7 and 5.7 microM with substrates, hippuryl-L-histidyl-L-leucine and angiotensin I, respectively. Tuna AI acetate (5.3 microM) also doubled the effect of bradykinin in the contraction of isolated guinea pig ileum[1].

Molecular Weight	1013.1
Formula	C46H68N12O14

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Kohama Y, et al. Biological properties of angiotensin-converting enzyme inhibitor derived from tuna muscle. J Pharmacobiodyn. 1989 Sep;12(9):566-71.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tuna AI acetate Inhibitor inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.