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Tuna AI acetate
🥰Excellent
Catalog No. T24906L
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
Tuna AI acetate
🥰Excellent
Purity: 98.49%
Catalog No. T24906L
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $117 | In Stock | |
| 2 mg | $165 | In Stock | |
| 5 mg | $262 | In Stock | |
| 10 mg | $388 | In Stock | |
| 25 mg | $592 | In Stock | |
| 50 mg | $828 | In Stock | |
| 100 mg | $1,110 | In Stock | |
| 200 mg | $1,480 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $460 | In Stock |
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Purity:98.49%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle. |
| Targets&IC50 | Ang I:5.7 μM(rabbit lung ACE), Hippuryl-L-histidyl-L-leucine:1.7 μM(rabbit lung ACE) |
| In vitro | Tuna AI acetate inhibited rabbit lung ACE non-competitively with Ki values of 1.7 and 5.7 microM with substrates, hippuryl-L-histidyl-L-leucine and angiotensin I, respectively. Tuna AI acetate (5.3 microM) also doubled the effect of bradykinin in the contraction of isolated guinea pig ileum[1]. |
| Molecular Weight | 1013.1 |
| Formula | C46H68N12O14 |
| Smiles | CC(O)=O.O=C(O)C[C@@H](C(O)=O)NC(CNC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CCCCN)NC([C@H]([C@@H](C)CC)NC([C@H](CC3=CNC=N3)NC([C@H]([C@H](O)C)NC([C@H]4NCCC4)=O)=O)=O)=O)=O)=O)=O |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (22.21 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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