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Thiazolinobutazone

Catalog No. T34846 CAS 54749-86-9

Synonyms: TZB, LAS 11871, LAS11871, LAS-11871

Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.

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Thiazolinobutazone, CAS 54749-86-9

Pack Size	Availability	Price/USD
5 mg	6-8 weeks	$ 970.00 $ 776.00
50 mg	6-8 weeks	$ 1,980.00 $ 1,584.00
100 mg	6-8 weeks	$ 2,500.00 $ 2,000.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.

Synonyms	TZB, LAS 11871, LAS11871, LAS-11871
Molecular Weight	410.53
Formula	C22H26N4O2S
CAS No.	54749-86-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Colombo M, Márquez M, Roberts DJ. Pharmacological properties of thiazolinobutazone (LAS 11 871). III. General pharmacology, ulcerogenic effects and acute toxicity. Arzneimittelforschung. 1976;26(7):1347-56. PubMed PMID: 1036923. 2. Márquez M, Roberts DJ. Pharmacological properties of thiazolinobutazone (LAS 11871). I. Anti-inflammatory effects. Arzneimittelforschung. 1974 Nov;24(11):1786-9. PubMed PMID: 4480050. 3. Márquez M, Roberts DJ. Pharmacological properties of thiazolinobutazone (LAS 11871). II. Analgesic and antipyretic effects. Arzneimittelforschung. 1974 Nov;24(11):1790-2. PubMed PMID: 4480051. 4. Moragues J, Thiele K, Márquez M, Colombo M, Roberts DJ. The preparation and pharmacological selection of a new anti-inflammatory agent, thiazolinobutazone. Arzneimittelforschung. 1974 Nov;24(11):1785-6. PubMed PMID: 4480049.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Thiazolinobutazone 54749-86-9 TZB LAS 11871 LAS11871 LAS-11871 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.