Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively ).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively ). |
Targets&IC50 | TGFβRI:2 nM |
In vitro | various cellular responses regulated by Transforming Growth Factor-β signaling such as cell proliferation, differentiation, cell migration and cell death. TGF-β has at least three isoforms TGF-β1, TGF-β2 and TGF-β3. TGF-β1 is two well-conserved single membrane serine/threonine kinase type I (ALK5). ALK5 inhibitos can be used for treating fibrotic disease, tumor, inflammatory disease, and autoimmune disease. |
Molecular Weight | 362.4 |
Formula | C20H14D3N5O2 |
CAS No. | 1950628-94-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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TGFβRI-IN-1 1950628-94-0 Stem Cells TGF-beta/Smad TGFβRIIN1 TGFβRI IN 1 TGFbetaRI-IN-1 TGFbRI-IN-1 inhibitor inhibit