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TAN67

Catalog No. T34784 CAS 1217628-73-3

Synonyms: SB-205607 dihydrobromide, SB 205607 dihydrobromide, SB205607 dihydrobromide, TAN-67, TAN 67

TAN67 is the first effective selective non-peptide delta1 opioid receptor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

TAN67, CAS 1217628-73-3

Pack Size	Availability	Price/USD	Quantity
10 mg	35 days	$ 875.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

TAN67 is the first effective selective non-peptide delta1 opioid receptor.

Synonyms	SB-205607 dihydrobromide, SB 205607 dihydrobromide, SB205607 dihydrobromide, TAN-67, TAN 67
Molecular Weight	506.282
Formula	C23H26Br2N2O
CAS No.	1217628-73-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Burford NT, Livingston KE, Canals M, Ryan MR, Budenholzer LM, Han Y, Shang Y, Herbst JJ, O'Connell J, Banks M, Zhang L, Filizola M, Bassoni DL, Wehrman TS, Christopoulos A, Traynor JR, Gerritz SW, Alt A. Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor. J Med Chem. 2015 May 28;58(10):4220-9. doi: 10.1021/acs.jmedchem.5b00007. Epub 2015 May 7. PubMed PMID: 25901762; PubMed Central PMCID: PMC4703104. 2. Martin NA, Prather PL. Interaction of co-expressed mu- and delta-opioid receptors in transfected rat pituitary GH(3) cells. Mol Pharmacol. 2001 Apr;59(4):774-83. PubMed PMID: 11259622. 3. Ohsawa M, Nagase H, Kamei J. Role of intracellular calcium in modification of mu and delta opioid receptor-mediated antinociception by diabetes in mice. J Pharmacol Exp Ther. 1998 Aug;286(2):780-7. PubMed PMID: 9694934. 4. Quock RM, Hosohata Y, Knapp RJ, Burkey TH, Hosohata K, Zhang X, Rice KC, Nagase H, Hruby VJ, Porreca F, Roeske WR, Yamamura HI. Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor. Eur J Pharmacol. 1997 May 12;326(1):101-4. PubMed PMID: 9178661.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

TAN67 1217628-73-3 SB-205607 Dihydrobromide SB205607 Dihydrobromide SB-205607 SB 205607 Dihydrobromide SB-205607 dihydrobromide SB 205607 dihydrobromide SB205607 dihydrobromide TAN-67 SB 205607 TAN 67 SB205607 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.