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Omadacycline mesylate

Catalog No. T5189L   CAS 1196800-40-4
Synonyms: PTK 0796, PTK-0796, PTK0796

Omadacycline is an aminomethylcycline antibiotic. Omadacycline demonstrated net cidal activity in relation to the initial burden against four strains of Streptococcus pneumoniae.

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Omadacycline mesylate Chemical Structure
Omadacycline mesylate, CAS 1196800-40-4
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Omadacycline is an aminomethylcycline antibiotic. Omadacycline demonstrated net cidal activity in relation to the initial burden against four strains of Streptococcus pneumoniae.
Synonyms PTK 0796, PTK-0796, PTK0796
Molecular Weight 652.76
Formula C30H44N4O10S
CAS No. 1196800-40-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Waites KB, Crabb DM, Liu Y, Duffy LB. In Vitro Activities of Omadacycline (PTK 0796) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7502-7504. Print 2016 Dec. PubMed PMID: 27671057; PubMed Central PMCID: PMC5119036. 2. Swathi CH, Chikala R, Ratnakar KS, Sritharan V. A structural, epidemiological & genetic overview of Klebsiella pneumoniae carbapenemases (KPCs). Indian J Med Res. 2016 Jul;144(1):21-31. doi: 10.4103/0971-5916.193279. Review. PubMed PMID: 27834322; PubMed Central PMCID: PMC5116894. 3. Lepak AJ, Zhao M, Marchillo K, VanHecker J, Andes DR. In Vivo Pharmacodynamic Evaluation of Omadacycline (PTK 0796) against Streptococcus pneumoniae in the Murine Pneumonia Model. Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02368-16. doi: 10.1128/AAC.02368-16. Print 2017 May. PubMed PMID: 28193651; PubMed Central PMCID: PMC5404567. 4. Török ME, Chapman AL, Lessing MP, Sanderson F, Seaton RA. Outpatient parenteral antimicrobial therapy: Recent developments and future prospects. Curr Opin Investig Drugs. 2010 Aug;11(8):929-39. Review. PubMed PMID: 20721835.

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Keywords

Omadacycline mesylate 1196800-40-4 PTK 0796 Omadacycline Mesylate PTK-0796 PTK0796 inhibitor inhibit

 

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