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Nikkomycin

Catalog No. T25870 CAS 77368-60-6

Synonyms: Nikkomycin I

Nikkomycin is used as an insecticide.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Nikkomycin, CAS 77368-60-6

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Nikkomycin is used as an insecticide.

Synonyms	Nikkomycin I
Molecular Weight	624.56
Formula	C25H32N6O13
CAS No.	77368-60-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Nesbitt JR, Steves EY, Schonhofer CR, Cait A, Manku SS, Yeung JHF, Bennet AJ, McNagny KM, Choy JC, Hughes MR, Moore MM. The Aspergillus fumigatus Sialidase (Kdnase) Contributes to Cell Wall Integrity and Virulence in Amphotericin B-Treated Mice. Front Microbiol. 2018 Jan 18;8:2706. doi: 10.3389/fmicb.2017.02706. eCollection 2017. PubMed PMID: 29403452; PubMed Central PMCID: PMC5778107. 2. Xu J, Zhang J, Zhuo J, Li Y, Tian Y, Tan H. Activation and mechanism of a cryptic oviedomycin gene cluster via the disruption of a global regulatory gene, adpA, in Streptomyces ansochromogenes. J Biol Chem. 2017 Dec 1;292(48):19708-19720. doi: 10.1074/jbc.M117.809145. Epub 2017 Sep 25. PubMed PMID: 28972184; PubMed Central PMCID: PMC5712612. 3. Healey KR, Nagasaki Y, Zimmerman M, Kordalewska M, Park S, Zhao Y, Perlin DS. The Gastrointestinal Tract Is a Major Source of Echinocandin Drug Resistance in a Murine Model of Candida glabrata Colonization and Systemic Dissemination. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01412-17. doi: 10.1128/AAC.01412-17. Print 2017 Dec. PubMed PMID: 28971865; PubMed Central PMCID: PMC5700336. 4. Zhuo J, Ma B, Xu J, Hu W, Zhang J, Tan H, Tian Y. Reconstruction of a hybrid nucleoside antibiotic gene cluster based on scarless modification of large DNA fragments. Sci China Life Sci. 2017 Sep;60(9):968-979. doi: 10.1007/s11427-017-9119-1. Epub 2017 Aug 21. PubMed PMID: 28840532.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Nikkomycin 77368-60-6 Nikkomycin I inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.