Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 57.00 | |
10 mg | In stock | $ 84.00 | |
25 mg | In stock | $ 139.00 | |
50 mg | In stock | $ 198.00 | |
100 mg | In stock | $ 369.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 71.00 |
Description | ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity |
In vitro | ML367, a probe molecule that has low micromolar inhibitory activity in the ATAD5 destabilizer screen run with 10 μM 5-fluorouridine (5-FUrd) as the DNA damaging agent. Interestingly, ML367 was found to block general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation. In this regard, the probe molecule could block DNA repair pathways that function upstream of ATAD5. |
Molecular Weight | 334.32 |
Formula | C19H12F2N4 |
CAS No. | 381168-77-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 120 mg/mL (358.94 mM)
You can also refer to dose conversion for different animals. More
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ML367 381168-77-0 Chromatin/Epigenetic Epigenetic Reader Domain inhibit Inhibitor ML 367 ML-367 inhibitor