Powder: -20°C for 3 years
In solvent: -80°C for 2 years
ML314 is an effective molecule agonist of NTR1 (EC50: 1.9 μM).
Description | ML314 is an effective molecule agonist of NTR1 (EC50: 1.9 μM). |
Targets&IC50 | NTR1:1.9 μM (EC50) |
In vitro | ML314 showed good selectivity against NTR2 and GPR35, but did not stimulate Ca2+ mobilization. ML314 is potentially a biased agonist operating via the β-arrestin pathway rather than the traditional Gq coupled pathway. |
Molecular Weight | 420.5 |
Formula | C24H28N4O3 |
CAS No. | 1448895-09-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 45 mg/mL (107.01 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML314 1448895-09-7 G蛋白偶联受体 Neurotensin Receptor ML-314 Inhibitor inhibitor inhibit