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DNA Damage/DNA Repair DNA/RNA Synthesis DTP3 TFA (1809784-29-9 free base)

DTP3 TFA (1809784-29-9 free base)

Catalog No. TP1430   CAS TP1430
Synonyms: DTP3 TFA,

DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.

DTP3 TFA (1809784-29-9 free base), CAS TP1430
Pack Size Availability Price/USD Quantity
5 mg In stock 145.00
10 mg In stock 255.00
25 mg In stock 410.00
50 mg In stock 690.00
100 mg In stock 870.00
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Purity 100.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.
Targets&IC50 GADD45β/MKK7,  
Synonyms DTP3 TFA ,
Purity 100.00%
Molecular Weight 639.62
Formula C28H36F3N7O7
CAS No. TP1430
Peptide Sequence NA

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: 50 mg/mL (78.17 mM), Need ultrasonic

H2O: 100 mg/mL (156.34 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Tornatore L, et al. Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7inhibitor and clinical candidate, DTP3. Toxicol Rep. 2019 Apr 19;6:369-379.

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.