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Brofaromine
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Catalog No. T10617Cas No. 63638-91-5
Alias CGP 11305A
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
Brofaromine
😃Good
Catalog No. T10617Alias CGP 11305ACas No. 63638-91-5
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $118 | 5 days | |
| 5 mg | $196 | 5 days | |
| 25 mg | $626 | 6-8 weeks | |
| 50 mg | $814 | 6-8 weeks | |
| 100 mg | $1,240 | 6-8 weeks | |
| 1 mL x 10 mM (in DMSO) | $222 | 5 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A). |
| Targets&IC50 | MAO-A:0.2 μM |
| In vitro | To assess whether the protective effect is related to MAO-A inhibition or another mechanism, the activity of Brofaromine on MAO-A in cultured cortical cells is determined. The cells exhibit significant MAO-A activity, which Brofaromine inhibits in a concentration-dependent manner (IC50: 0.19 μM; Hill coefficient: 0.96), with nearly complete inhibition at 10 μM. The IC50 range of Brofaromine is 0.01 μM to 0.1 μM. |
| Alias | CGP 11305A |
| Molecular Weight | 310.19 |
| Formula | C14H16BrNO2 |
| Cas No. | 63638-91-5 |
| Relative Density. | 1.386 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (805.96 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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