Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
Description | Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A). |
Targets&IC50 | MAO-A:0.2 μM |
In vitro | In order to assess whether the protective effect is related to the inhibition of the MAO-A or due to another mechanism, the effect of Brofaromine is determined on the activity of MAO-A in cultured cortical cells. The cultured cortical cells have significant MAO-A activity. Brofaromine inhibits the enzyme in a concentration-dependent manner (IC50: 0.19?μM). Hill coefficient is 0.96. The enzyme is almost completely inhibited at 10?μM. Brofaromine inhibits MAO-A activity of our cultured cortical cells in a concentration-dependent manner. The IC50 range of Brofaromine is 0.01?μM to 0.1?μM. |
Synonyms | CGP 11305A |
Molecular Weight | 310.19 |
Formula | C14H16BrNO2 |
CAS No. | 63638-91-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 250 mg/mL (805.96 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Brofaromine 63638-91-5 代谢 神经科学 MAO CGP 11305A Inhibitor inhibitor inhibit