Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 52.00 | |
5 mg | In stock | $ 123.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 455.00 | |
50 mg | In stock | $ 787.00 | |
100 mg | In stock | $ 1,360.00 | |
500 mg | In stock | $ 2,720.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 135.00 |
Description | BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer. |
Targets&IC50 | MRCKβ (SCC12 cells):64 nM, MRCKα/β:(ki)0.0136 nM/0.0233 nM, MRCKα/β:0.0136 nM/0.0233 nM ( Ki) |
In vitro | Among over 750 human cancer cell lines tested, BDP9066 consistently exhibited anti-proliferative activity in hematologic cancer cells[1]. |
In vivo | As an effective and selective MRCK inhibitor, BDP9066, in a two-stage chemical carcinogenesis model of mouse squamous cell carcinoma, reduced MRCKα S1003 phosphorylation and the growth of skin tumors with local treatment. |
Molecular Weight | 348.44 |
Formula | C20H24N6 |
CAS No. | 2226507-04-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8 mg/mL (22.96 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BDP9066 2226507-04-4 Cell Cycle/Checkpoint Cytoskeletal Signaling Stem Cells ROCK BDP 9066 BDP-9066 inhibitor inhibit