Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BB-78485 is a potent small molecule inhibitor of LpxC metalloenzymes with antibacterial activity. The IC50 value of BB-78485 against LpxC is 160 nM. BB-78485 can be used for the study of Gram-negative bacterial infections.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 328.00 | |
5 mg | In stock | $ 783.00 | |
10 mg | In stock | $ 1,080.00 | |
25 mg | In stock | $ 1,570.00 | |
50 mg | In stock | $ 1,970.00 | |
100 mg | In stock | $ 2,480.00 | |
500 mg | In stock | $ 4,910.00 |
Description | BB-78485 is a potent small molecule inhibitor of LpxC metalloenzymes with antibacterial activity. The IC50 value of BB-78485 against LpxC is 160 nM. BB-78485 can be used for the study of Gram-negative bacterial infections. |
Targets&IC50 | LpxC:160 nM |
In vitro | BB-78485 can inhibit LpxC with an IC50 value of 160 nM[1].BB-78485 is effective against D21 and D22 (lpxC101), with MIC values of 2 μg/mL and 0.016 μg/mL, respectively[1].The MIC values of BB-78485 against Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae, and Burkholderia cepacia range from 1 μg/mL to 32 μg/mL[1]. |
Synonyms | BB78485, BB 78485 |
Molecular Weight | 420.48 |
Formula | C23H20N2O4S |
CAS No. | 207732-11-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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