Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 10-14 weeks | $ 347.00 | |
25 mg | 10-14 weeks | $ 987.00 | |
50 mg | 10-14 weeks | $ 1,360.00 | |
100 mg | 10-14 weeks | $ 2,190.00 | |
1 mL * 10 mM (in DMSO) | 10-14 weeks | $ 346.00 |
Description | Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM. |
Targets&IC50 | P. falciparum (W2):1.1 nM, P. falciparum (Ro73):1.1 nM |
In vitro | Arterolane (also known as Trioxolane 7; OZ277; RBx-11160) exhibits inhibitory effects on a variety of Plasmodium falciparum strains, demonstrating IC50 values as follows: 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL against P. falciparum strains K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20 respectively. Furthermore, this antimalarial agent shows potent efficacy with IC50s of 1.1 nM (0.43 ng/mL) against both P. falciparum strains Ro73 and W2. |
Synonyms | OZ 277, RBx 11160 |
Molecular Weight | 392.53 |
Formula | C22H36N2O4 |
CAS No. | 664338-39-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (254.76 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Arterolane 664338-39-0 Others OZ-277 OZ 277 OZ277 RBx 11160 inhibitor inhibit