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Antide acetate

Catalog No. T9380L CAS T9380L

Synonyms: Antide acetate (112568-12-4 Free base)

Antide acetate is an LHRH antagonist and represses LH and FSH release from the pituitary gland.

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Antide acetate, CAS T9380L

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Antide acetate is an LHRH antagonist and represses LH and FSH release from the pituitary gland.

In vivo

Analogs of GnRH, including agonists (GnRH-a) and antagonists (GnRH-ant), have been widely used to inhibit gonadotropin pituitary release.?Aside from the effect of GnRH analogs on the pituitary-gonadal axis, studies have shown that GnRH has extrapituitary effects, particularly on rat and human ovaries.?In the present study, we evaluated the direct in vivo effects of the GnRH-a, leuprolide acetate (LA), or the GnRH-ant, Antide (Ant), either singly or together, on ovarian follicular development in prepubertal eCG-treated rats.

Synonyms	Antide acetate (112568-12-4 Free base)
Molecular Weight	1651.34
Formula	C84H112ClN17O16
CAS No.	T9380L

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Fernanda P , Griselda I , Alejandra V , et al. Gonadotropin-Releasing Hormone Antagonist Antide Inhibits Apoptosis of Preovulatory Follicle Cells in Rat Ovary[J]. Biology of Reproduction(3):659-666.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Antide acetate T9380L Endocrinology/Hormones LHRH Antide acetate (112568-12-4 Free base) Inhibitor inhibitor inhibit

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