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AM-3102

Catalog No. T29938   CAS 213182-22-0
Synonyms: KDS-5104, AM 3102, Methyl oleoylethanolamide

AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.

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AM-3102 Chemical Structure
AM-3102, CAS 213182-22-0
Pack Size Availability Price/USD Quantity
5 mg 35 days $ 110.00
10 mg 35 days $ 210.00
50 mg 35 days $ 853.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.
Synonyms KDS-5104, AM 3102, Methyl oleoylethanolamide
Molecular Weight 339.56
Formula C21H41NO2
CAS No. 213182-22-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Orio L, Alen F, Pavón FJ, Serrano A, García-Bueno B. Oleoylethanolamide, Neuroinflammation, and Alcohol Abuse. Front Mol Neurosci. 2019 Jan 9;11:490. doi: 10.3389/fnmol.2018.00490. eCollection 2018. Review. PubMed PMID: 30687006; PubMed Central PMCID: PMC6333756. 2. Bowen KJ, Kris-Etherton PM, Shearer GC, West SG, Reddivari L, Jones PJH. Oleic acid-derived oleoylethanolamide: A nutritional science perspective. Prog Lipid Res. 2017 Jul;67:1-15. doi: 10.1016/j.plipres.2017.04.001. Epub 2017 Apr 5. Review. PubMed PMID: 28389247. 3. Brown JD, Karimian Azari E, Ayala JE. Oleoylethanolamide: A fat ally in the fight against obesity. Physiol Behav. 2017 Jul 1;176:50-58. doi: 10.1016/j.physbeh.2017.02.034. Epub 2017 Feb 27. Review. PubMed PMID: 28254531. 4. Zhou H, Yang WS, Li Y, Ren T, Peng L, Guo H, Liu JF, Zhou Y, Zhao Y, Yang LC, Jin X. Oleoylethanolamide attenuates apoptosis by inhibiting the TLR4/NF-κB and ERK1/2 signaling pathways in mice with acute ischemic stroke. Naunyn Schmiedebergs Arch Pharmacol. 2017 Jan;390(1):77-84. doi: 10.1007/s00210-016-1309-4. Epub 2016 Oct 13. PubMed PMID: 27738712.

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Keywords

AM-3102 213182-22-0 KDS-5104 AM3102 KDS 5104 KDS5104 AM 3102 Methyl oleoylethanolamide inhibitor inhibit

 

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