Shopping Cart
- Remove All
Your shopping cart is currently empty
ADRA1D receptor antagonist 1 HCl
🥰Excellent
Catalog No. T10250Cas No. 1191908-14-1
Alias ADRA1D receptor antagonist 1 HCl(1191908-24-3 free base)
ADRA1D receptor antagonist 1 HCl is an orally active, potent and selective α1D adrenergic receptor antagonist (Ki: 1.6 nM) with potential antiproliferative activity.
ADRA1D receptor antagonist 1 HCl
🥰Excellent
Purity: 98.13%
Catalog No. T10250Alias ADRA1D receptor antagonist 1 HCl(1191908-24-3 free base)Cas No. 1191908-14-1
ADRA1D receptor antagonist 1 HCl is an orally active, potent and selective α1D adrenergic receptor antagonist (Ki: 1.6 nM) with potential antiproliferative activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $199 | In Stock |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreBatch Information
Select Batch
Purity:98.13%
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
| Description | ADRA1D receptor antagonist 1 HCl is an orally active, potent and selective α1D adrenergic receptor antagonist (Ki: 1.6 nM) with potential antiproliferative activity. |
| Targets&IC50 | α1D-adrenoceptor:1.6 nM (Ki) |
| In vitro | ADRA1D receptor antagonist 1 exhibits low hERG inhibition and higher selectivity for α1D-AR over α1A- and α1B-ARs, without affecting α1A- and α1B-ARs[1]. |
| In vivo | In the rat model of bladder outlet obstruction (BOO), ADRA1D receptor antagonist 1 (4.4 µg/kg; intravenous injection) dose-dependently decreased the occurrence of non-voiding bladder contractions during the urinary storage phase[1]. |
| Animal Research | Animal Model: Rat with bladder outlet obstruction (BOO). Dosage: 4.4 μg/kg. Administration: Intravenous injection |
| Synonyms | ADRA1D receptor antagonist 1 HCl(1191908-24-3 free base) |
| Molecular Weight | 337.2 |
| Formula | C15H14Cl2N4O |
| Cas No. | 1191908-14-1 |
| Smiles | Cl.C[C@H](c1cccc(c1)C#N)n1cc(Cl)cc(C(N)=O)c1=N |
| Relative Density. | no data available |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (237.25 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy ADRA1D receptor antagonist 1 HCl | purchase ADRA1D receptor antagonist 1 HCl | ADRA1D receptor antagonist 1 HCl cost | order ADRA1D receptor antagonist 1 HCl | ADRA1D receptor antagonist 1 HCl chemical structure | ADRA1D receptor antagonist 1 HCl in vivo | ADRA1D receptor antagonist 1 HCl in vitro | ADRA1D receptor antagonist 1 HCl formula | ADRA1D receptor antagonist 1 HCl molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.