Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-Acolbifene (EM-343) is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogenic activities. (Rac)-Acolbifene contains a piperidine ring and exhibits good pharmacological profile,relative binding affinity (RBA)=380.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 54.00 | |
5 mg | In stock | $ 123.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 452.00 | |
50 mg | In stock | $ 665.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 123.00 |
Description | (Rac)-Acolbifene (EM-343) is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogenic activities. (Rac)-Acolbifene contains a piperidine ring and exhibits good pharmacological profile,relative binding affinity (RBA)=380. |
In vitro | In T-47D cells, (Rac)-Acolbifene (0.110 nM) inhibits cell growth with an IC50 value of 0.110 nM[1]. |
In vivo | In ovariectomized mice, (Rac)-Acolbifene (7.5 nM, 75 nM; oral) shows shows 63% and 84% antiuterotrophic inhibitions, respectively[1]. |
Synonyms | (Rac)-EM-652, EM-343 |
Molecular Weight | 457.56 |
Formula | C29H31NO4 |
CAS No. | 151533-34-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (196.7 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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(Rac)-Acolbifene 151533-34-5 Endocrinology/Hormones Estrogen Receptor/ERR EM-652 (Rac)-EM-652 EM 343 EM-343 EM652 Acolbifene EM 652 EM343 inhibitor inhibit